Inter-individual variability in atrasentan exposure partly explains variability in kidney protection and fluid retention responses: A post hoc analysis of the SONAR trial.
Jeroen V KoomenJasper StevensGeorge L BakrisRicardo Correa-RotterFan Fan HouDalane W KitzmanDonald KohanHirofumi MakinoJohn Joseph Valentine McMurrayHans-Henrik ParvingVlado PerkovicSheldon W TobeDick de ZeeuwHiddo J Lambers HeerspinkPublished in: Diabetes, obesity & metabolism (2020)
Atrasentan plasma exposure varied among individual patients and partially explained between-patient variability in efficacy and safety response.