Liver inflammation is common and linked to metabolic derangements in persons with treated HIV.

Kara W ChewKunling WuKatherine TassiopoulosFrank J PalellaSusanna NaggieNetanya S UtayEdgar T OvertonMark Sulkowski

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)

ALT elevation was common in this cohort of PWH and associated with metabolic disease and hepatic steatosis markers. Nonalcoholic fatty liver disease is likely a common cause of liver inflammation in PWH receiving suppressive antiretrovirals, deserving targeted diagnosis and intervention.

Keyphrases

oxidative stress
antiretroviral therapy
randomized controlled trial
hiv positive
hiv infected
human immunodeficiency virus
hepatitis c virus
hiv aids
hiv testing
men who have sex with men
liver fibrosis