Etidronate down-regulates Toll-like receptor 2 ligand-induced chemokine production by inhibiting MyD88 expression and NF-κB activation.
Naohito YambeRiyoko TamaiIzumi MashimaYusuke KiyouraPublished in: Immunopharmacology and immunotoxicology (2020)
Etidronate down-regulates IL-8 and MCP-1 production in U937 cells by inhibiting both the expression of MyD88 and activation of NF-κB p65 in the TLR2, but not TLR4, pathway.