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CDK9 inhibitors downregulate DKK1 expression to suppress the metastatic potential of HCC cells.

Mijin ParkJin Hwa ChoByul MoonJeong-Hoon KimJung-Ae Kim
Published in: Genes & genomics (2023)
Taken together, our findings suggest that CDK9 inhibitors are potent tools to target DKK1, which can suppress the metastatic progression of HCC.
Keyphrases
  • squamous cell carcinoma
  • small cell lung cancer
  • cell cycle
  • induced apoptosis
  • poor prognosis
  • cell cycle arrest
  • risk assessment
  • human health
  • oxidative stress
  • cell death
  • cell proliferation
  • climate change
  • pi k akt