In silico design and in vitro expression of novel multiepitope DNA constructs based on HIV-1 proteins and Hsp70 T-cell epitopes.

Elahe AkbariKimia KardaniAli NamvarSoheila AjdaryEsmat Mirabzadeh ArdakaniVahid KhalajAzam Bolhassani

Published in: Biotechnology letters (2021)

The combined in silico/in vitro methods indicated two multiepitope constructs can be produced and used as probable effective immunogens for HIV-1 vaccine development.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
hiv testing
human immunodeficiency virus
hepatitis c virus
hiv aids
molecular docking
men who have sex with men
poor prognosis
south africa
heat shock protein
cell free
single molecule
heat shock