Does in vitro fertilization affect the expression of miRNAs and their biogenesis pathway in preimplantation mouse embryos?
Elham AziziMarefat Ghaffari NovinMohammad NajiFardin AmidiZahra Shams MofarahePublished in: Birth defects research (2019)
Downregulation of let-7a and developmental related transcription factor, Stat3, in IVF mouse blastocysts may affect preimplantation development and implantation of embryos. Moreover, the genes of the miRNA biogenesis pathway were not changed in preimplantation mouse embryos through the IVF procedure.