Prognostic Value of β-Catenin and L1CAM Expressions in Type I Endometrial Carcinoma.

Yolanda ManuleUpik Anderiani MiskadRina MasadahBerti NelwanMuhammad Husni CangaraMardiati Mardiati

Published in: Asian Pacific journal of cancer prevention : APJCP (2023)

This study suggest that the positive expression of β-catenin together with L1CAM can participate in the development of tumor cells in type I Endometrial Carcinoma, in its ability to involve lymphovascular space invasion, and metastases to other sites. Our results indicate that both of β-catenin and L1CAM are prominent biomarkers for the prognosis of type I Endometrial Carcinoma.

Keyphrases

endometrial cancer
epithelial mesenchymal transition
cell proliferation
poor prognosis
signaling pathway
binding protein