Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme).

Helen BlackshawJane VennikCarl PhilpottMike ThomasCaroline EylesJames CarpenterCaroline S ClarkeSteve MorrisAnne SchilderValerie LundPaul LittleStephen DurhamSpiros DenaxasElizabeth WilliamsonDavid BeardJonathan CookSteffi Le ConteKim AireyJim BoardmanClaire Hopkins

Published in: Trials (2019)

The expert panel review process resulted in agreement on key elements and an optimal design for the MACRO trial, considered most likely to be successful in terms of both recruitment potential and ability to establish best management of patients with CRS.

Keyphrases

chronic rhinosinusitis
study protocol
clinical practice
clinical trial
phase iii
randomized controlled trial
phase ii
open label
climate change
double blind