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Repurposing carbamazepine for the treatment of amyotrophic lateral sclerosis in SOD1-G93A mouse model.

Jing-Jing ZhangQin-Ming ZhouSheng ChenWei-Dong Le
Published in: CNS neuroscience & therapeutics (2018)
Our findings uncovered the therapeutic effects of CBZ against disease pathogenesis in SOD1-G93A mice, indicating a promising clinical utilization of CBZ in ALS therapy.
Keyphrases
  • amyotrophic lateral sclerosis
  • mouse model
  • high fat diet induced
  • type diabetes
  • chemotherapy induced