Wei-Dong Le (Weidong Le)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 59

Top Venues

CNS neuroscience & therapeutics

Nature communications

Neuroscience bulletin

Molecular neurodegeneration

Baylor College of Medicine

Shanghai Jiao Tong University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Baylor College of Medicine Dec 28 2005 - Jul 30 2013

United States

Professor :: Neurology

Education History

Shanghai Jiao Tong University Sep 01 1984 - Aug 30 1988

China

PHD :: Neurology

Publications

Huai-Bin Cai, Jie Dong, Lupeng Wang, Breanna Sullivan, Lixin Sun, Lisa Chang, Victor Martinez Smith, Jinhui Ding, Wei-Dong Le, Charles R Gerfen
Patch and matrix striatonigral neurons differentially regulate locomotion. Research square (2024)
Congcong Jia, Lulu Tian, Cheng Cheng, Jun Zhang, Murad Al-Nusaif, Tianbai Li, Huijia Yang, Yushan Lin, Song Li, Wei-Dong Le
α-Synuclein reduces acetylserotonin O-methyltransferase mediated melatonin biosynthesis by microtubule-associated protein 1 light chain 3 beta-related degradation pathway. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Jinjian Hu, Wencheng Xia, Shuyi Zeng, Yeh-Jun Lim, Youqi Tao, Yunpeng Sun, Lang Zhao, Haosen Wang, Wei-Dong Le, Dan Li, Shengnan Zhang, Cong Liu, Yan-Mei Li
Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures. Nature communications 15 (1) (2024)
Panpan Wang, Yaping Shao, Murad Al-Nusaif, Jun Zhang, Huijia Yang, Yuting Yang, Kunhyok Kim, Song Li, Cong Liu, Huaibin Cai, Wei-Dong Le
Pathological characteristics of axons and alterations of proteomic and lipidomic profiles in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency. Molecular neurodegeneration 19 (1) (2024)
Huai-Bin Cai, Jie Dong, Lupeng Wang, Breanna Sullivan, Lixin Sun, Lisa Chang, Victor Martinez Smith, Jinhui Ding, Wei-Dong Le, Charles R Gerfen
Patch and matrix striatonigral neurons differentially regulate locomotion. Research square (2024)
Panpan Wang, Yaping Shao, Murad Al-Nusaif, Jun Zhang, Huijia Yang, Yuting Yang, Kunhyok Kim, Song Li, Cong Liu, Huaibin Cai, Wei-Dong Le
Pathological characteristics of axons and alterations of proteomic and lipidomic profiles in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency. Molecular neurodegeneration 19 (1) (2024)
Xiao Huang, Jialing Zhao, Yan-Jiang Wang, Tingqi Yan, Shu Gou, Xiaofeng Zhu, Liu Yang, Fang Ye, Jie Zhang, Yanjiang Wang, Shaojie Yang, Wei-Dong Le, Yang Xiang
Association between plasma CTRPs with cognitive impairment and neurodegeneration of Alzheimer's disease. CNS neuroscience & therapeutics 30 (2) (2024)
Panpan Wang, Yaping Shao, Murad Al-Nusaif, Jun Zhang, Huijia Yang, Yuting Yang, Kunhyok Kim, Song Li, Cong Liu, Huaibin Cai, Wei-Dong Le
Pathological characteristics of axons and alterations of proteomic and lipidomic profiles in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency. Molecular neurodegeneration 19 (1) (2024)
Huijia Yang, Yaping Shao, Yiying Hu, Jin Qian, Panpan Wang, Lulu Tian, Yang Ni, Song Li, Murad Al-Nusaif, Cong Liu, Wei-Dong Le
Fecal microbiota from patients with Parkinson's disease intensifies inflammation and neurodegeneration in A53T mice. CNS neuroscience & therapeutics 30 (8) (2024)
Xiao Huang, Jialing Zhao, Yan-Jiang Wang, Tingqi Yan, Shu Gou, Xiaofeng Zhu, Liu Yang, Fang Ye, Jie Zhang, Yanjiang Wang, Shaojie Yang, Wei-Dong Le, Yang Xiang
Association between plasma CTRPs with cognitive impairment and neurodegeneration of Alzheimer's disease. CNS neuroscience & therapeutics 30 (2) (2024)
Huijia Yang, Yaping Shao, Yiying Hu, Jin Qian, Panpan Wang, Lulu Tian, Yang Ni, Song Li, Murad Al-Nusaif, Cong Liu, Wei-Dong Le
Fecal microbiota from patients with Parkinson's disease intensifies inflammation and neurodegeneration in A53T mice. CNS neuroscience & therapeutics 30 (8) (2024)
Xiao Huang, Jialing Zhao, Yan-Jiang Wang, Tingqi Yan, Shu Gou, Xiaofeng Zhu, Liu Yang, Fang Ye, Jie Zhang, Yanjiang Wang, Shaojie Yang, Wei-Dong Le, Yang Xiang
Association between plasma CTRPs with cognitive impairment and neurodegeneration of Alzheimer's disease. CNS neuroscience & therapeutics 30 (2) (2024)
Jinjian Hu, Wencheng Xia, Shuyi Zeng, Yeh-Jun Lim, Youqi Tao, Yunpeng Sun, Lang Zhao, Haosen Wang, Wei-Dong Le, Dan Li, Shengnan Zhang, Cong Liu, Yan-Mei Li
Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures. Nature communications 15 (1) (2024)
Hong Zhang, Huazhang Guo, Danni Li, Yiling Zhang, Shengnan Zhang, Wenyan Kang, Cong Liu, Wei-Dong Le, Liang Wang, Dan Li, Bin Dai
Halogen doped graphene quantum dots modulate TDP-43 phase separation and aggregation in the nucleus. Nature communications 15 (1) (2024)
Yiying Hu, Huijia Yang, Chunli Song, Lulu Tian, Panpan Wang, Tianbai Li, Cheng Cheng, Murad AlNusaif, Song Li, Zhanhua Liang, Wei-Dong Le
LRRK2 G2019S Gene Mutation Causes Skeletal Muscle Impairment in Animal Model of Parkinson's Disease. Journal of cachexia, sarcopenia and muscle (2024)
Panpan Wang, Yaping Shao, Murad Al-Nusaif, Jun Zhang, Huijia Yang, Yuting Yang, Kunhyok Kim, Song Li, Cong Liu, Huaibin Cai, Wei-Dong Le
Pathological characteristics of axons and alterations of proteomic and lipidomic profiles in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency. Molecular neurodegeneration 19 (1) (2024)
Congcong Jia, Lulu Tian, Cheng Cheng, Jun Zhang, Murad Al-Nusaif, Tianbai Li, Huijia Yang, Yushan Lin, Song Li, Wei-Dong Le
α-Synuclein reduces acetylserotonin O-methyltransferase mediated melatonin biosynthesis by microtubule-associated protein 1 light chain 3 beta-related degradation pathway. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Hong Zhang, Huazhang Guo, Danni Li, Yiling Zhang, Shengnan Zhang, Wenyan Kang, Cong Liu, Wei-Dong Le, Liang Wang, Dan Li, Bin Dai
Halogen doped graphene quantum dots modulate TDP-43 phase separation and aggregation in the nucleus. Nature communications 15 (1) (2024)
Jinjian Hu, Wencheng Xia, Shuyi Zeng, Yeh-Jun Lim, Youqi Tao, Yunpeng Sun, Lang Zhao, Haosen Wang, Wei-Dong Le, Dan Li, Shengnan Zhang, Cong Liu, Yan-Mei Li
Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures. Nature communications 15 (1) (2024)
Hong Zhang, Huazhang Guo, Danni Li, Yiling Zhang, Shengnan Zhang, Wenyan Kang, Cong Liu, Wei-Dong Le, Liang Wang, Dan Li, Bin Dai
Halogen doped graphene quantum dots modulate TDP-43 phase separation and aggregation in the nucleus. Nature communications 15 (1) (2024)
Xiao Huang, Jialing Zhao, Yan-Jiang Wang, Tingqi Yan, Shu Gou, Xiaofeng Zhu, Liu Yang, Fang Ye, Jie Zhang, Yanjiang Wang, Shaojie Yang, Wei-Dong Le, Yang Xiang
Association between plasma CTRPs with cognitive impairment and neurodegeneration of Alzheimer's disease. CNS neuroscience & therapeutics 30 (2) (2024)
Congcong Jia, Lulu Tian, Cheng Cheng, Jun Zhang, Murad Al-Nusaif, Tianbai Li, Huijia Yang, Yushan Lin, Song Li, Wei-Dong Le
α-Synuclein reduces acetylserotonin O-methyltransferase mediated melatonin biosynthesis by microtubule-associated protein 1 light chain 3 beta-related degradation pathway. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Qiu-Qin Han, Wei-Dong Le
NLRP3 Inflammasome-Mediated Neuroinflammation and Related Mitochondrial Impairment in Parkinson's Disease. Neuroscience bulletin (2023)
Zhaofei Yang, Ying Wang, Min Wei, Song Li, Congcong Jia, Cheng Cheng, Murad Al-Nusaif, Jun Zhang, Cong Liu, Wei-Dong Le
Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain. Cell death & disease 14 (1) (2023)
Hui Xu, Jin Wang, Murad Al-Nusaif, Huipeng Ma, Wei-Dong Le
CCL2 promotes metastasis and epithelial-mesenchymal transition of non-small cell lung cancer via PI3K/Akt/mTOR and autophagy pathways. Cell proliferation (2023)
Manli Wang, Xi Chen, Long Niu, Jianli Xu, Hang Yu, Xiaojiao Xu, Qiu Yang, Yang Xiang, Wei-Dong Le
APP swe /PS1 ΔE9 mice exhibit low oxygen saturation and alterations of erythrocytes preceding the neuropathology and cognitive deficiency during Alzheimer's disease. CNS neuroscience & therapeutics (2023)
Yaping Shao, Zhenfa Fu, Yanfeng Wang, Zhaofei Yang, Yushan Lin, Song Li, Cheng Cheng, Min Wei, Zheyi Liu, Guo-Wang Xu, Wei-Dong Le
A metabolome atlas of mouse brain on the global metabolic signature dynamics following short-term fasting. Signal transduction and targeted therapy 8 (1) (2023)
Zhaofei Yang, Ying Wang, Min Wei, Song Li, Congcong Jia, Cheng Cheng, Murad Al-Nusaif, Jun Zhang, Cong Liu, Wei-Dong Le
Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain. Cell death & disease 14 (1) (2023)
Jun Zhang, Yixin Chen, Yarui Zhao, Panpan Wang, Hongbin Ding, Cong Liu, Junhong Lü, Wei-Dong Le
Terahertz Irradiation Improves Cognitive Impairments and Attenuates Alzheimer's Neuropathology in the APP SWE /PS1 DE9 Mouse: A Novel Therapeutic Intervention for Alzheimer's Disease. Neuroscience bulletin (2023)
Min Wei, Zhaofei Yang, Song Li, Wei-Dong Le
Nanotherapeutic and Stem Cell Therapeutic Strategies in Neurodegenerative Diseases: A Promising Therapeutic Approach. International journal of nanomedicine 18 (2023)
Lu He, Qinming Zhou, Chaoyang Xiu, Yaping Shao, Dingding Shen, Huanyu Meng, Wei-Dong Le, Sheng Chen
Circulating proteomic biomarkers for diagnosing sporadic amyotrophic lateral sclerosis: a cross-sectional study. Neural regeneration research 19 (8) (2023)
Zhaofei Yang, Ying Wang, Min Wei, Song Li, Congcong Jia, Cheng Cheng, Murad Al-Nusaif, Jun Zhang, Cong Liu, Wei-Dong Le
Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain. Cell death & disease 14 (1) (2023)
Lu He, Qinming Zhou, Chaoyang Xiu, Yaping Shao, Dingding Shen, Huanyu Meng, Wei-Dong Le, Sheng Chen
Circulating proteomic biomarkers for diagnosing sporadic amyotrophic lateral sclerosis: a cross-sectional study. Neural regeneration research 19 (8) (2023)
Wei-Dong Le, Panpan Wang, Murad Al-Nusaif, Jun Zhang, Huijia Yang, Yuting Yang, Kunhyok Kim, Song Li, Cong Liu, Huaibin Cai
Pathological characteristics of axons and proteome patterns in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency. Research square (2023)
Lu He, Qinming Zhou, Chaoyang Xiu, Yaping Shao, Dingding Shen, Huanyu Meng, Wei-Dong Le, Sheng Chen
Circulating proteomic biomarkers for diagnosing sporadic amyotrophic lateral sclerosis: a cross-sectional study. Neural regeneration research 19 (8) (2023)
Min Wei, Zhaofei Yang, Song Li, Wei-Dong Le
Nanotherapeutic and Stem Cell Therapeutic Strategies in Neurodegenerative Diseases: A Promising Therapeutic Approach. International journal of nanomedicine 18 (2023)
Min Wei, Zhaofei Yang, Song Li, Wei-Dong Le
Nanotherapeutic and Stem Cell Therapeutic Strategies in Neurodegenerative Diseases: A Promising Therapeutic Approach. International journal of nanomedicine 18 (2023)
Zhaofei Yang, Ying Wang, Min Wei, Song Li, Congcong Jia, Cheng Cheng, Murad Al-Nusaif, Jun Zhang, Cong Liu, Wei-Dong Le
Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain. Cell death & disease 14 (1) (2023)
Tianbai Li, Wei-Dong Le, Abhishek Lenka
Linking the cerebellum to Parkinson disease: an update. Nature reviews. Neurology (2023)
Lu He, Qinming Zhou, Chaoyang Xiu, Yaping Shao, Dingding Shen, Huanyu Meng, Wei-Dong Le, Sheng Chen
Circulating proteomic biomarkers for diagnosing sporadic amyotrophic lateral sclerosis: a cross-sectional study. Neural regeneration research 19 (8) (2023)
Zhaofei Yang, Ying Wang, Min Wei, Song Li, Congcong Jia, Cheng Cheng, Murad Al-Nusaif, Jun Zhang, Cong Liu, Wei-Dong Le
Intrastriatal injection of Parkinson's disease intestine and vagus lysates initiates α-synucleinopathy in rat brain. Cell death & disease 14 (1) (2023)
Xinyao Liu, Hang Yu, Yuanyuan Wang, Song Li, Cheng Cheng, Murad Al-Nusaif, Wei-Dong Le
Altered Motor Performance, Sleep EEG, and Parkinson's Disease Pathology Induced by Chronic Sleep Deprivation in Lrrk2 G2019S Mice. Neuroscience bulletin 38 (10) (2022)
Murad Al-Nusaif, Yuting Yang, Song Li, Cheng Cheng, Wei-Dong Le
The role of NURR1 in metabolic abnormalities of Parkinson's disease. Molecular neurodegeneration 17 (1) (2022)
Youqi Tao, Yunpeng Sun, Shiran Lv, Wencheng Xia, Kun Zhao, Qianhui Xu, Qinyue Zhao, Lin He, Wei-Dong Le, Yong Wang, Cong Liu, Dan Li
Heparin induces α-synuclein to form new fibril polymorphs with attenuated neuropathology. Nature communications 13 (1) (2022)
Rong Zhang, Xiaojiao Xu, Hang Yu, Xiaolan Xu, Manli Wang, Wei-Dong Le
Factors Influencing Alzheimer's Disease Risk: Whether and How They are Related to the APOE Genotype. Neuroscience bulletin 38 (7) (2022)
Shuai Huang, Xinxin Liu, Dan Liu, Xiaozhe Zhang, Lihua Zhang, Wei-Dong Le, Yukui Zhang
Pyrylium-Based Derivatization for Rapid Labeling and Enhanced Detection of Cholesterol in Mass Spectrometry Imaging. Journal of the American Society for Mass Spectrometry 33 (12) (2022)
Yufei Liu, Long Niu, Xinyao Liu, Cheng Cheng, Wei-Dong Le
Recent Progress in Non-motor Features of Parkinson's Disease with a Focus on Circadian Rhythm Dysregulation. Neuroscience bulletin 37 (7) (2021)
Ying Wang, Xi Chen, Yuanyuan Wang, Song Li, Huai-Bin Cai, Wei-Dong Le
The essential role of transcription factor Pitx3 in preventing mesodiencephalic dopaminergic neurodegeneration and maintaining neuronal subtype identities during aging. Cell death & disease 12 (11) (2021)
Song Li, Congcong Jia, Tianbai Li, Wei-Dong Le
Hot Topics in Recent Parkinson's Disease Research: Where We are and Where We Should Go. Neuroscience bulletin 37 (12) (2021)
Yaping Shao, Tianbai Li, Zheyi Liu, Xiaolin Wang, Xiaojiao Xu, Song Li, Guowang Xu, Wei-Dong Le
Comprehensive metabolic profiling of Parkinson's disease by liquid chromatography-mass spectrometry. Molecular neurodegeneration 16 (1) (2021)
Long Niu, Feng Zhang, Xiaojiao Xu, Yuting Yang, Song Li, Hui Liu, Wei-Dong Le
Chronic sleep deprivation altered the expression of circadian clock genes and aggravated Alzheimer's disease neuropathology. Brain pathology (Zurich, Switzerland) (2021)
Jie Dong, Xinyao Liu, Yuanyuan Wang, Huaibin Cai, Wei-Dong Le
Nurr1Cd11bcre conditional knockout mice display inflammatory injury to nigrostriatal dopaminergic neurons. Glia 68 (10) (2020)
Zhaofei Yang, Tianbai Li, Song Li, Min Wei, Hongqian Qi, Bai-Rong Shen, Raymond Chuen-Chung Chang, Wei-Dong Le, Fengyuan Piao
Altered Expression Levels of MicroRNA-132 and Nurr1 in Peripheral Blood of Parkinson's Disease: Potential Disease Biomarkers. ACS chemical neuroscience 10 (5) (2019)
Hai-Yan Shang, Jing-Jing Zhang, Zhen-Fa Fu, Yu-Fei Liu, Song Li, Sheng Chen, Wei-Dong Le
Therapeutic effects of hirsutella sinensis on the disease onset and progression of amyotrophic lateral sclerosis in SOD1G93A transgenic mouse model. CNS neuroscience & therapeutics 26 (1) (2019)
Tianbai Li, Wei-Dong Le
Biomarkers for Parkinson's Disease: How Good Are They? Neuroscience bulletin 36 (2) (2019)
Feng Zhang, Long Niu, Song Li, Wei-Dong Le
Pathological Impacts of Chronic Hypoxia on Alzheimer's Disease. ACS chemical neuroscience 10 (2) (2018)
Jing-Jing Zhang, Qin-Ming Zhou, Sheng Chen, Wei-Dong Le
Repurposing carbamazepine for the treatment of amyotrophic lateral sclerosis in SOD1-G93A mouse model. CNS neuroscience & therapeutics 24 (12) (2018)
Fang Guo, Xinyao Liu, Huaibin Cai, Wei-Dong Le
Autophagy in neurodegenerative diseases: pathogenesis and therapy. Brain pathology (Zurich, Switzerland) 28 (1) (2017)
Qin-Ming Zhou, Jing-Jing Zhang, Song Li, Sheng Chen, Wei-Dong Le
n-butylidenephthalide treatment prolongs life span and attenuates motor neuron loss in SOD1G93A mouse model of amyotrophic lateral sclerosis. CNS neuroscience & therapeutics 23 (5) (2017)

Wei-Dong Le.css-eqlu8i{font-size:small;padding-left:4px;} (Weidong Le)

Publication Activity (10 Years)

Top Topics

Top Venues

Wei-Dong Le (Weidong Le)