A double-blind, randomized, placebo-controlled pilot trial to evaluate safety and efficacy of vorapaxar on arteriovenous fistula maturation.

Christoph B OlivierVandana SundaramGlenn M ChertowSumana ShashidharLori K McDonnellVictoria Y DingManisha DesaiKenneth W MahaffeyMatthew Mell

Published in: The journal of vascular access (2019)

Fewer than half of participants had functional maturation within 180 days after surgery, suggesting a major need for agents or strategies that enhance arteriovenous fistula maturation.

Keyphrases

placebo controlled
double blind
phase iii
phase ii
clinical trial
open label
randomized controlled trial
radiation therapy
locally advanced