There is limited evidence to demonstrate that a drug holiday is unnecessary (and may in fact be potentially harmful) in dental practice. Primary closure and antibacterial prophylaxis are recommended despite limited evidences. All evidence have been graded as either of a low or very low quality, and thus further high-quality randomized controlled trials are needed to answer this clinical question.
Keyphrases
- end stage renal disease
- randomized controlled trial
- healthcare
- newly diagnosed
- chronic kidney disease
- primary care
- high resolution
- emergency department
- quality improvement
- clinical trial
- systematic review
- patient reported outcomes
- mass spectrometry
- study protocol
- oral health
- anti inflammatory
- electronic health record