Comparison between midazolam and propofol in acute phase for ventilated patients with sepsis: a post-hoc analysis of the DESIRE trial.

Noriko Miyagawa Yu Kawazoe Tetsuya Sato Shigeki Kushimoto Kyohei MiyamotoYoshinori OhtaTakeshi MorimotoHitoshi Yamamuranull null

Published in: Acute medicine & surgery (2022)

In patients with sepsis required mechanical ventilation, sedation with midazolam based on a light sedation protocol may be associated with inappropriate sedation during the acute phase, with increased coma and delirium as compared to propofol.

Keyphrases

mechanical ventilation
intensive care unit
acute respiratory distress syndrome
respiratory failure
acute kidney injury
septic shock
extracorporeal membrane oxygenation
randomized controlled trial
cardiac surgery
clinical trial
study protocol
phase iii
double blind
placebo controlled