Distinguishing glutamate and glutamine in in vivo 1 H MRS based on nuclear spin singlet order filtering.
Jia-Xiang XinDa-Xiu WeiYan RenJun-Long WangGuang YangHuojun ZhangJianqi LiCaixia FuYe-Feng YaoPublished in: Magnetic resonance in medicine (2022)
H-MR signals of Glu and Gln in human brains in vivo. The optimal control method provides an effective way to prepare the SSO of a specific spin system with high efficiency and in turn selectively probe the signals of a targeted molecule.
Keyphrases
- high efficiency
- living cells
- room temperature
- density functional theory
- single molecule
- endothelial cells
- fluorescent probe
- induced pluripotent stem cells
- quantum dots
- transition metal
- cancer therapy
- sensitive detection
- pluripotent stem cells
- magnetic resonance
- contrast enhanced
- computed tomography
- magnetic resonance imaging
- molecular dynamics