Immediate radiotherapy versus observation in patients with node-positive prostate cancer after radical prostatectomy.

Christian SchauflerSumedh KaulAaron FleishmanRuslan KoretsPeter ChangAndrew WagnerSimon KimJoaquim BellmuntIrving KaplanAria F Olumi Boris Gershman

Published in: Prostate cancer and prostatic diseases (2022)

In observational analyses designed to emulate a hypothetical target trial of aRT versus observation in pN1 prostate cancer, aRT was associated with improved OS only for men with Gleason 8-10 disease, ≥2 positive LNs, or negative surgical margins.

Keyphrases

radical prostatectomy
prostate cancer
hiv infected
early stage
antiretroviral therapy
clinical trial
lymph node
study protocol
radiation therapy
randomized controlled trial
middle aged
locally advanced
phase ii
squamous cell carcinoma
open label