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Single-cell RNA sequencing of human non-hematopoietic bone marrow cells reveals a unique set of inter-species conserved biomarkers for native mesenchymal stromal cells.

Loïc FiévetNicolas EspagnolleDaniela GerovskaDavid BernardCharlotte SyrykhCamille LaurentPierre LayrolleJulien De LimaArthur JustoNicolas ReinaLouis CasteillaMarcos J Araúzo-BravoAbderrahim NajiJean-Christophe PagèsFrédéric Deschaseaux
Published in: Stem cell research & therapy (2023)
Overall, our taxonomy for native BM non-hematopoietic compartment provides an explicit depiction of gene expression in human ECs, MCs and MSCs at single-cell resolution. This analysis helps enhance our understanding of the phenotype and the complexity of biological functions of native human BM-MSCs.
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