Oncogenic effect of PHLDB2 is associated with epithelial-mesenchymal transition and E-cadherin regulation in colorectal cancer.

Geng ChenTong ZhouTantan MaTingting CaoZhenxiang Yu

Published in: Cancer cell international (2019)

Our findings suggest that PHLDB2 is a downstream effector of EMT pathway and may present as an important biomarker for colon cancer prognosis and a target for colon cancer intervention.

Keyphrases

epithelial mesenchymal transition
transforming growth factor
randomized controlled trial
signaling pathway
regulatory t cells
dendritic cells
immune response
type iii