The substance P/ neurokinin-1 receptor signaling pathway mediates metastasis in human colorectal SW480 cancer cells.

Malihe GolestanehMohsen FiroozraiHossein JavidSeyed Isaac Hashemy

Published in: Molecular biology reports (2022)

According to the results, the SP/NKR1 signaling pathway can be considered one of the main metastatic effectors in human colorectal cancer. Therefore, AP might be suggested to be used as the SP antagonist and an efficient anti-metastatic drug.

Keyphrases

signaling pathway
endothelial cells
squamous cell carcinoma
small cell lung cancer
pi k akt
induced pluripotent stem cells
pluripotent stem cells
epithelial mesenchymal transition
transcription factor
emergency department
cell proliferation
electronic health record