Megasphaera in the Stool Microbiota Is Negatively Associated With Diarrheal Cryptosporidiosis.
Maureen A CareyGregory L MedlockMasud AlamMamun KabirMd Jashim UddinUma NayakJason PapinA S G FaruqueRashidul HaqueWilliam A PetriCarol A GilchristPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Microbiome composition broadly, and specifically low Megasphaera abundance, was associated with diarrheal symptoms prior to and at the time of Cryptosporidium detection. This observation suggests that the gut microenvironment may play a role in determining the severity of a Cryptosporidium infection. Clinical Trials Registration. NCT02764918.