Effect of bone sialoprotein coating on progression of bone formation in a femoral defect model in rats.

Anja KleinAndreas BaranowskiUlrike RitzChristiane MackHermann GötzEva LangendorfBilal Al-NawasPhilipp DreesPol M RommensAlexander Hofmann

Published in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2019)

A significant superiority of BSP-coated scaffolds over uncoated scaffolds could not be proven. However, BSP-coating showed a tendency towards improving bone ingrowth in the scaffolds 4 weeks after implantation. This effect was only short-lived: bone growth in the control scaffolds tended to outpace that of the BSP-group at week eight.

Keyphrases

tissue engineering
bone mineral density
soft tissue
bone loss
postmenopausal women
randomized controlled trial
study protocol
preterm birth