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Impact of Anesthetic Agents on Endothelial Glycocalyx Injury during Total Knee Arthroplasty: Desflurane- vs. Propofol-Based Anesthesia-A Prospective Randomized Controlled Trial.

Seung Hyun LeeJi Min ChoiEun Hi ParkLiyun PiaoHyun-Jun ParkKa-Young RheeSeong-Hyop Kim
Published in: BioMed research international (2021)
The effect of desflurane was not superior to that of propofol in protecting the EG from ischemia-reperfusion injury during total knee arthroplasty. This trial is registered with Trial Registry Number NCT02756715 (http://clinicaltrials.gov).
Keyphrases
  • total knee arthroplasty
  • study protocol
  • randomized controlled trial
  • total hip
  • ischemia reperfusion injury
  • phase iii
  • clinical trial
  • phase ii
  • oxidative stress
  • endothelial cells
  • open label
  • placebo controlled