Zishen Huoxue Recipe Protecting Mitochondrial Function of Hypoxic/Reoxygenated Myocardial Cells through mTORC1 Signaling Pathway.
Ruxiu LiuXing ChangJie LiYao ShunyuPublished in: Evidence-based complementary and alternative medicine : eCAM (2020)
ZSHX Decoction has the effects of activating mTORC1, inhibiting the overexpression of 4E-BP1, inhibiting fatty acid oxidation, protecting the respiratory function of mitochondria, reducing ROS and apoptosis, and thus protecting myocardial cells from injury.
Keyphrases
- signaling pathway
- cell cycle arrest
- induced apoptosis
- pi k akt
- cell death
- fatty acid
- left ventricular
- endoplasmic reticulum stress
- epithelial mesenchymal transition
- reactive oxygen species
- oxidative stress
- cell proliferation
- dna damage
- hydrogen peroxide
- heart failure
- transcription factor
- atrial fibrillation
- respiratory tract
- endoplasmic reticulum