Role of PRY-1/Axin in heterochronic miRNA-mediated seam cell development.
Avijit MallickAyush RanawadeBhagwati P GuptaPublished in: BMC developmental biology (2019)
Our results show that PRY-1 plays a conserved role to maintain normal expression of heterochronic miRNAs in nematodes. Furthermore, we demonstrated that PRY-1 acts upstream of the WNT asymmetry pathway components WRM-1, LIT-1, and POP-1, and miRNA target genes in seam cell development.