CD4 count recovery and associated factors among individuals enrolled in the South African antiretroviral therapy programme: An analysis of national laboratory based data.
Tendesayi Kufa-ChakezhaZara ShubberWilliam B MacLeodSimbarashe TakuvaSergio CarmonaJacob BorMarelize GorgensYogan PillayAdrian PurenJeffrey W EatonNicole Fraser-HurtPublished in: PloS one (2019)
For individuals starting with ART with severe immunosuppression, CD4 recovery to 200cells/μl did not occur or took longer than 12 month for significant proportions. CD4 monitoring and interventions recommended for advanced HIV disease should continue until full recovery.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv aids
- hiv infected patients
- induced apoptosis
- nk cells
- randomized controlled trial
- electronic health record
- physical activity
- early onset
- cell cycle arrest
- study protocol
- big data
- clinical trial
- peripheral blood
- cell death
- endoplasmic reticulum stress
- signaling pathway
- data analysis