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Efficacy and tolerability of sodium-glucose co-transporter-2 inhibitors and glucagon-like peptide-1 receptor agonists: A systematic review and network meta-analysis.

Humaira HusseinFrancesco ZaccardiKamlesh Khunti F MedSciMelanie Jane DaviesEmily PatskoNafeesa N DhalwaniDavid E KloeckerEkaterini IoannidouLaura J Gray
Published in: Diabetes, obesity & metabolism (2020)
Long-acting GLP-1RAs showed superiority in reducing HbA1c levels, body weight and waist circumference. SGLT-2is showed reductions in blood pressure levels. This review provides essential evidence to guide treatment recommendations in the management of type 2 diabetes.
Keyphrases
  • body weight
  • blood pressure
  • body mass index
  • open label
  • randomized controlled trial
  • hypertensive patients
  • adipose tissue
  • study protocol
  • double blind
  • wild type
  • replacement therapy