Upregulation of Wnt2b exerts neuroprotective effect by alleviating mitochondrial dysfunction in Alzheimer's disease.

Ling-Zhi XuBing-Qiu LiFang-Yu LiMei-Na QuanWei QinYing LiWen-Wen LiYu ZhaoYi-Ping WeiJian-Ping Jia

Published in: CNS neuroscience & therapeutics (2023)

Our study highlights that Wnt2b decline is associated with cognitive impairment in AD, and upregulation of Wnt2b can exert neuroprotective effects in AD, particularly in ameliorating mitochondrial dysfunction.

Keyphrases

cell proliferation
cognitive impairment
stem cells
poor prognosis
cognitive decline
long non coding rna