Upregulation of cluster of differentiation 36 mRNA expression in peripheral blood mononuclear cells correlates with frailty severity in older adults.

Chung-Sheng LeeChin-Hao ChangChin-Ying ChenChih-Yuan ShihJen-Kuei PengHsien-Liang HuangPei-Yun ChenTse-Le HuangChing-Yu ChenJaw-Shiun Tsai

Published in: Journal of cachexia, sarcopenia and muscle (2022)

CD36 mRNA levels in PBMCs in robust older adults are significantly lower than in pre-frail and in frail. Our findings suggest that CD36 mRNA levels in PBMCs may be considered a potential biomarker for frail severity.

Keyphrases

community dwelling
physical activity
binding protein
nk cells
cell proliferation
poor prognosis