Risk factors for liposomal bupivacaine resistance after total hip or knee arthroplasties: a retrospective observational cohort in 237 patients.
Scott BuzinArianna L GianakosDeborah LiAnthony ViolaSherif ElkattawyDavid M KellerRichard S YoonFrank A LiporacePublished in: Patient safety in surgery (2020)
We identify risk factors for resistance to liposomal bupivacaine, which include younger age less than 64 years old, history of smoking/pain management/opioid use. Future studies should use these risk factors as exclusion criteria when using liposomal bupivacaine or initiating any randomized trials regarding efficacy.
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