Endoplasmic Reticulum Stress Promotes Telomerase Reverse Transcriptase Expression Contributes to Development of Allergic Rhinitis.

Yun LiaoXiwen ZhangShuang TaoShiqi WangQinmiao HuangPing TangAifa TangPing-Chang YangGui Yang

Published in: American journal of rhinology & allergy (2024)

T cells of subjects with AR. Telomerase promoted Th2 cell polarization by inducing Foxp3 protein degradation and promotes GATA3 activation. Inhibition of TERT or eIF2a alleviated experimental AR.

Keyphrases

endoplasmic reticulum stress
allergic rhinitis
induced apoptosis
poor prognosis
regulatory t cells
single cell
transcription factor
cell therapy
amino acid
long non coding rna