Login / Signup

Proteomic analysis reveals changes in energy metabolism of skeletal muscle in beef cattle supplemented with vitamin A.

Carolina F CamposThaís C CostaRafael Torres de Souza RodriguesSimone E F GuimarãesFelipe H MouraWalmir SilvaMario L ChizzottiPedro V R PaulinoPedro D B BenedetiFabyano F SilvaMarcio de Souza Duarte
Published in: Journal of the science of food and agriculture (2020)
Vitamin A supplementation at fattening phase impairs intramuscular fat deposition in beef cattle likely by changing the energy metabolism of skeletal muscle. The interaction of retinoic acid and heat shock 70-kDa protein may play a pivotal role in intramuscular fat deposition as a consequence of vitamin A supplementation by impairing de novo fatty acid synthesis as a result of a possible decrease in insulin sensitivity in the skeletal muscle. © 2020 Society of Chemical Industry.
Keyphrases
  • skeletal muscle
  • heat shock
  • fatty acid
  • insulin resistance
  • heat shock protein
  • adipose tissue
  • heat stress
  • type diabetes
  • amino acid
  • binding protein