Why clinical trials in disc regeneration strive to achieve completion: Insights from publication status and funding sources.

Luca AmbrosioGiorgia PetrucciFabrizio RussoClaudia CicioneRocco PapaliaGianluca VadalàVincenzo Denaro

Published in: JOR spine (2024)

Most clinical trials exploring cell-based disc regenerative therapies for chronic LBP have never reached completion, with only a small fraction reporting preliminary data in publications.

Keyphrases

clinical trial
stem cells
cell therapy
phase ii
mesenchymal stem cells
electronic health record
drinking water
open label
phase iii
double blind
adverse drug
study protocol
big data
emergency department
randomized controlled trial
machine learning
tissue engineering
wound healing