Representativeness of Participants in the ACCORD Trial Compared to Middle-aged and Older Adults Living with Diabetes in the United States.

Ryo IkesuYingyan WuScott C ZimmermanKosuke InouePeter ButoMelinda C PowerCatherine A SchaeferM Maria GlymourElizabeth Rose Mayeda

Published in: Epidemiology (Cambridge, Mass.) (2024)

ACCORD represented a minority of US middle-aged and older adults with diabetes. Given the differential risk profile between ACCORD participants and the general population with diabetes, extrapolating the trial findings may not be appropriate.

Keyphrases

type diabetes
cardiovascular disease
glycemic control
study protocol
physical activity
phase iii
clinical trial
phase ii
randomized controlled trial
adipose tissue
weight loss
open label
skeletal muscle
placebo controlled