Red Cell Distribution Width and Absolute Lymphocyte Count Associate With Biomarkers of Inflammation and Subsequent Mortality in Rheumatoid Arthritis.
Alyssa LangeLenche KostadinovaSofi DamjanovskaIbtissam GadSameena SyedHusna SiddiquiPatrick YousifCorinne M KowalCarey ShiveChristopher BurantNora SingerTaissa BejSadeer Al-KindiBrigid WilsonMaya MattarDavid A ZidarDonald D AnthonyPublished in: The Journal of rheumatology (2022)
RDW and ALC before disease-modifying antirheumatic drug therapy are associated with biomarkers of monocyte/macrophage inflammation and subsequent mortality. The mechanistic linkage between TNF signaling and lymphopenia found here warrants further investigation.
Keyphrases
- rheumatoid arthritis
- oxidative stress
- peripheral blood
- cardiovascular events
- disease activity
- cell therapy
- single cell
- dendritic cells
- interstitial lung disease
- ankylosing spondylitis
- stem cells
- endothelial cells
- cardiovascular disease
- genome wide
- emergency department
- coronary artery disease
- rheumatoid arthritis patients
- dna methylation
- gene expression
- systemic sclerosis
- systemic lupus erythematosus
- hiv testing
- immune response
- men who have sex with men