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Granulocyte-colony stimulating factor does not prevent in vitro cisplatin-induced germ cell reduction in immature human and mouse testis.

Gabriele MatilionyteGrace ForsythJingtao GuoMichael P RimmerBrian P HermannRichard A AndersonRod Thomas Mitchell
Published in: BMC cancer (2023)
This study demonstrates that exposure to G-CSF does not prevent cisplatin-induced germ cell loss in immature human and mouse testicular tissues in an in vitro system.
Keyphrases
  • germ cell
  • endothelial cells
  • induced pluripotent stem cells
  • pluripotent stem cells
  • gene expression