Value and potential limitations of vertebral fracture assessment (VFA) compared to conventional spine radiography: experience from a fracture liaison service (FLS) and a meta-analysis.

F MalgoN A T HamdyC H J M TichelerF SmitH M KroonT J RabelinkO M DekkersN M Appelman-Dijkstra

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2017)

Our findings from the meta-analysis suggest an adequate performance of VFA for the detection of vertebral fractures. However, we could not demonstrate these findings in our center, especially the specificity. Our data advocate caution with exclusively relying on VFA in the assessment of vertebral fractures without identifying performance and potential limitations of the technique.

Keyphrases

bone mineral density
systematic review
healthcare
mental health
human health
postmenopausal women
electronic health record
meta analyses
randomized controlled trial
risk assessment
body composition
machine learning
computed tomography
loop mediated isothermal amplification
data analysis
structural basis