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An overview of the recent progress in Middle East Respiratory Syndrome Coronavirus (MERS-CoV) drug discovery.

Mahmoud Kandeel
Published in: Expert opinion on drug discovery (2023)
Research on discovering drugs that can inhibit MERS-CoV started at a slow pace, and although efforts have steadily increased, clinical trials for new drugs specifically targeting MERS-CoV have not been extensive enough. The explosion in efforts to find new medications for the SARS-CoV-2 virus indirectly enhanced the volume of data on MERS-CoV inhibition by including MERS-CoV in drug assays. The appearance of COVID-19 completely transformed the data available on MERS-CoV inhibition. Despite the fact that new infected cases are constantly being diagnosed, there are currently no approved vaccines for or inhibitors of MERS-CoV.
Keyphrases
  • respiratory syndrome coronavirus
  • sars cov
  • coronavirus disease
  • drug discovery
  • clinical trial
  • emergency department
  • high throughput
  • drug delivery
  • randomized controlled trial
  • drug induced
  • deep learning
  • phase ii