Clinical development of anticancer drugs can be enhanced using efficacy data of small population clinical trials.
Keiichi SawachiNaoki MatsumaruKatsura TsukamotoPublished in: Journal of clinical pharmacy and therapeutics (2022)
Even when the sample size of the clinical trial was increased, the efficacy data of anticancer drugs could not be changed significantly. These results supported the accelerated approval pathway based on the promising efficacy data of small populations in anticancer drug development.