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Reversal of albuminuria by combined AM6545 and perindopril therapy in experimental diabetic nephropathy.

Federica BaruttaStefania BelliniRaffaella MastrocolaR GambinoFabiana PiscitelliVincenzo Di MarzoBeatrice CorbettaV Kiran VemuriAlexandros MakriyannisLaura AnnaratoneGraziella BrunoGabriella Gruden
Published in: British journal of pharmacology (2018)
Peripheral CB1 receptor blockade used as add-on treatment to ACE-inhibition reverses albuminuria, nephrin loss and inflammation in DM.
Keyphrases
  • diabetic nephropathy
  • oxidative stress
  • angiotensin ii
  • stem cells
  • angiotensin converting enzyme
  • blood pressure
  • mesenchymal stem cells
  • replacement therapy
  • binding protein
  • glycemic control