Effects of treatment with hydroxychloroquine on the modulation of Th17/Treg ratio and pregnancy outcomes in women with recurrent implantation failure: clinical trial.
Sonia SadeghpourMorteza Ghasemnejad BerenjiHamid NazarianTohid GhasemnejadMohammad Hadi NematollahiSina AbroonShahrokh PaktinatHeidar Heidari KhoeiHojjat Ghasemnejad BerenjiMarefat Ghaffari NovinPublished in: Immunopharmacology and immunotoxicology (2020)
Our results demonstrated that the administration of HCQ in RIF women with immune cell disorders during pregnancy could affect the Th17/Treg ratio and enhance Treg and diminish Th17 responses which may be associated with successful pregnancy outcomes. However, significant difference in pregnancy outcomes was not observed in the present study.