Direct acylation and alkynylation of hydrocarbons via synergistic decatungstate photo-HAT/nickel catalysis.

Herein, we describe a protocol for the direct and selective acylation and alkynylation of the C(sp 3 )-H bonds of saturated hydrocarbons by synergistic decatungstate photo-HAT and nickel catalysis. This method, using cheap and easy-to-synthesize TBADT as a HAT photocatalyst, exhibits excellent site selectivity. A wide variety of high-value ketones, amides, esters, and diverse alkynes can be efficiently constructed from abundant hydrocarbon feedstocks.