Alterations in expression of α1-adrenergic receptors possibly are involved in prevention of age-associated apoptosis in rat hippocampus by treadmill exercise.

Leila ChodariMaedeh GhasemiNasrin Mehranfard

Published in: Journal of complementary & integrative medicine (2023)

Our study suggests that manipulations attenuating α1-AR activity, including nonselective α1-adrenergic antagonists, may protect against hippocampal neurodegeneration in aging brains.

Keyphrases

oxidative stress
poor prognosis
cerebral ischemia
high intensity
endoplasmic reticulum stress
cell death
physical activity
cell cycle arrest
binding protein
cognitive impairment
long non coding rna
resistance training
blood brain barrier