Polygenic risk, familial liability and stress reactivity in psychosis: an experience sampling study.
Anita SchickRuud van WinkelBochao D LinJurjen J LuykxSonja M C de ZwarteKristel R van Eijknull nullInez Myin-GermeysUlrich ReininghausPublished in: Psychological medicine (2022)
This tentatively suggests that polygenic risk may operate in different ways than previously assumed and amplify reactivity to stress in unaffected individuals but operate as a resilience factor in relatives by attenuating their stress reactivity.