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Tolerability of N-chlorotaurine in comparison with routinely used antiseptics: an in vitro study on chondrocytes.

Magdalena PilzKevin StaatsOjan AssadianReinhard WindhagerJohannes Holinka
Published in: Pharmacological reports : PR (2024)
(3%), for which a significant decrease in cell viability was detected. Considering that the in vivo tolerability is usually significantly higher, our findings could be an indication that cartilage tissue in vivo would tolerate the already clinically used 1% NCT solution. In combination with the broad-spectrum bactericidal activity, NCT may be a promising antiseptic for the treatment of septic joint infections.
Keyphrases
  • open label
  • extracellular matrix
  • acute kidney injury
  • double blind
  • randomized controlled trial
  • clinical trial
  • combination therapy
  • clinical evaluation