Anticancer potential of Ferula hezarlalehzarica Y. Ajani fraction in Raji lymphoma cell line: induction of apoptosis, cell cycle arrest, and changes in mitochondrial membrane potential.

Yahya AsemaniAbbas AzadmehrReza HajiaghaeeZahra Amirghofran

Published in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2018)

The F. hezarlalehzarica hexane fraction induced apoptosis in Raji cells by changing the expression of apoptosis-related genes, cell cycle distribution, and MMP. These data suggested a potential effectiveness of F. hezarlalehzarica for inducing cell death in lymphoma cells. Graphical abstract ᅟ.

Keyphrases

cell cycle arrest
cell death
induced apoptosis
pi k akt
cell cycle
endoplasmic reticulum stress
oxidative stress
signaling pathway
cell proliferation
diffuse large b cell lymphoma
systematic review
poor prognosis
machine learning
electronic health record
binding protein
artificial intelligence