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Electrospun Nanofibers for Wound Management.

Johnson V JohnAlec McCarthyAnik KaranJingwei Xie
Published in: ChemNanoMat : chemistry of nanomaterials for energy, biology and more (2021)
Electrospun nanofibers show great potential in biomedical applications. This mini review article traces the recent advances in electrospun nanofibers for wound management via various approaches. Initially, we provide a short note on the four phases of wound healing, including hemostasis, inflammation, proliferation, and remodeling. Then, we state how the nanofiber dressings can stop bleeding and reduce the pain. Following that, we discuss the delivery of therapeutics and cells using different types of nanofibers for enhancing cell migration, angiogenesis, and re-epithelialization, resulting in the promotion of wound healing. Finally, we present the conclusions and future perspectives regarding the use of electrospun nanofibers for wound management.
Keyphrases
  • wound healing
  • cell migration
  • oxidative stress
  • induced apoptosis
  • signaling pathway
  • small molecule
  • atrial fibrillation
  • cell cycle arrest
  • tissue engineering
  • lactic acid
  • cell death
  • vascular endothelial growth factor