Coding Variants are Relevant to the Expression of Obesity-Related Genes for Pediatric Adiposity.

Ke MaoMeixian ZhangJinshuai CaoXiaoyuan ZhaoLiwang GaoLiwan FuHong ChengChun YanXiaopeng XuXiaofeng ShiZhuoyuan JiangBingqing WangYong-Biao Zhang Jie Mi

Published in: Obesity (Silver Spring, Md.) (2021)

This work identified two coding variants that were significantly associated with pediatric adiposity and were expression quantitative trait loci for obesity-related genes. This study provides new insights into the pathophysiology of Chinese childhood obesity.

Keyphrases

insulin resistance
weight gain
poor prognosis
metabolic syndrome
weight loss
copy number
high fat diet induced
type diabetes
genome wide
adipose tissue
skeletal muscle
binding protein
body mass index
high resolution
gene expression
physical activity
mass spectrometry
childhood cancer
genome wide association