Pericortical Enhancement on Delayed Postgadolinium Fluid-Attenuated Inversion Recovery Images in Normal Aging, Mild Cognitive Impairment, and Alzheimer Disease.

Whitney M Freeze R S Schnerr W M Palm Jacobus F A Jansen Heidi I L Jacobs Erik Hoff Frans Rochus Josef Verhey Walter H Backes

Published in: AJNR. American journal of neuroradiology (2017)

Postcontrast pericortical enhancement on FLAIR images occurs in older individuals with normal cognition, mild cognitive impairment, and dementia. It may represent chronic focal superficial BBB leakage. Future longitudinal studies are needed to determine its clinical significance.

Keyphrases

mild cognitive impairment
cognitive decline
deep learning
convolutional neural network
optical coherence tomography
blood brain barrier
physical activity
current status
community dwelling
cross sectional
case control
magnetic resonance imaging
machine learning
multiple sclerosis
computed tomography
white matter