Long-term effectiveness and safety of ustekinumab in bio-naïve and bio-experienced anti-tumor necrosis factor patients with Crohn's disease: a real-world multicenter Brazilian study.
Rogério Serafim ParraJúlio Maria Fonseca ChebliNatália Sousa Freitas QueirozAderson Omar Mourão Cintra DamiãoMatheus Freitas Cardoso de AzevedoLiliana Andrade ChebliErika Ruback BertgesAntonio José Tiburcio Alves JuniorOrlando Ambrogini JuniorBianca Loyo Pona Schiavetti da SilvaMarcio LubiniMauro BafuttoCristina FloresEduardo Garcia VilelaSandra Felice BorattoNewton Luiz Tricarico Gasparetti JuniorFlavio SteinwurzNayara Salgado CarvalhoOmar FéresJosé Joaquim Ribeiro da RochaPublished in: BMC gastroenterology (2022)
UST therapy was effective and safe in the long term in this large real-life cohort of Brazilian patients with refractory CD, regardless of previous exposure to other biological agents.