In Vitro Infant Fecal Fermentation Characteristics of Human Milk Oligosaccharides Were Controlled by Initial Microbiota Composition More than Chemical Structure.

Shiqi XuJonathan A LaneJuchun ChenYuxing ZhengHongwei WangXiong FuQiang HuangSushil DhitalFeitong LiuBin Zhang

Published in: Molecular nutrition & food research (2022)

The findings demonstrate that short-term in vitro fermentation outcomes largely depend on the initial gut microbiota composition more than the impact of HMO molecular specificity. These results advance the current understanding for the design of personalized infant nutritional solutions and therapies in future.

Keyphrases

human milk
low birth weight
saccharomyces cerevisiae
lactic acid
preterm infants
preterm birth
single molecule
metabolic syndrome
skeletal muscle