Long-term Safety of Treatment with Autologous Mesenchymal Stem Cells in Patients with Radiation-Induced Xerostomia: Primary Results of the MESRIX Phase I/II Randomized Trial.

Charlotte Duch LynggaardChristian GrønhøjSiri Beier JensenRobin ChristensenLena SpechtElo AndersenTobias Thostrup Andersen Urszula Maria CiochonGulla S RathjeAdam Espe Hansen Helene StampeAnne Fischer-NielsenChristian von Buchwald

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Our data show that ASC therapy is safe with a clinically relevant effect on xerostomia-related symptoms. Confirmation in larger randomized controlled trials is warranted.

Keyphrases

radiation induced
mesenchymal stem cells
radiation therapy
randomized controlled trial
bone marrow
cell therapy
electronic health record
umbilical cord
big data
machine learning
physical activity
combination therapy
platelet rich plasma
depressive symptoms
deep learning
drug induced
data analysis